As there are several indications for the existence of so-called "Dark Matter" (DM) from an astrophysical point of view, direct detection of a candidate particle in a lab has not been successful this far. A set of direct detection experiments, which use different targets, could potentially test the various types of DM interactions with different properties of nuclei. To connect possible future measurements of DM signals to a candidate DM particle, these DM experimental signals must be propagated through nuclear cores — composed of many protons and neutrons — to the fundamental level of the DM theory. Due to the complexity in describing the many-body nucleus, this propagation has historically been done in a model- dependent fashion. As a candidate for propagating possible experimental data to the level of protons and neutrons, Nuclear Lattice Effective Field Theory (NLEFT) provides an approach which systematically enables the reduction of uncertainties.